MPIALIGN

NAME

mpialign − parallel local alignment of biological sequences

SYNOPSIS

mpialign [−s scores] [−S split] [−H hblk] [−V vblk] file1 file2

DESCRIPTION

mpiAlign is a local sequence aligner, especially intended for use with large biological DNA sequences, with more than 1Mbp (Millions of base pairs). It uses the Smith-Waterman exact algorithm with affine gap cost function to perform this task.

General options:

−s <scores>

specify a comma−separated list of scores to be used while calculating aligment matrices throughout the program. The list must be in the format "−sMATCH,MISMATCH,GAP_OPEN,GAP_EXTENSION" (without quotes), and is parsed in this PRECISE order; no spaces are allowed between values. If there are any unspecified parameters, these are set to default values and a warning message is issued; exceeding parameters are discarded

Stage 2 options:
−S <split>

(mpialign only) number of parts in which to split the alignment matrix; after this step a cyclic block model is applied, subdividing each part equally between all available nodes

−H <hblk>

(mpialign only) number of horizontal subdivisions made by each node to its alignment submatrix; since this value defines block width, a good choice should allow two full matrix lines to fit the processor’s cache pages, improving algorithm performance

−V <vblk>

(mpialign only) number of vertical subdivisions made by each node to its alignment submatrix; this value directly affects the amount of internode communication and is used ONLY if ’split’ is set to 1, otherwise it is set to the number of available nodes